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  • Title: Absence of structural rearrangements of chromosome 11 in human primary malignant melanoma.
    Author: Nedoszytko B, Mrózek K, Limon J.
    Journal: Cancer Genet Cytogenet; 1992 Feb; 58(2):196-7. PubMed ID: 1551088.
    Abstract:
    Cytogenetic analysis of 10 primary and 18 metastatic malignant melanomas revealed that structural abnormalities of chromosome 11 were present in 50% of metastatic lesions and were not found in primary tumors. Our findings suggest that chromosome 11 aberrations represent secondary changes in malignant melanoma tumorigenesis.
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