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  • Title: [Life style, Chlamydia trachomatis infection, bacterial vaginosis and their impact on the frequency of cervical lesions].
    Author: Zbroch T, Knapp P, Błońska E, Kobylec M, Knapp P.
    Journal: Ginekol Pol; 2004 Jul; 75(7):538-44. PubMed ID: 15517774.
    Abstract:
    OBJECTIVES: Sexually transmitted infectious factors attained unquestionable importance in the initiation of the cervical intraepithelial neoplasia. The aim of this study was to evaluate the incidence and impact of Bacterial vaginosis, Chlamydia trachomatis infection in accordance to a life style on clinically and cytologically evaluated cervical lesions. DESIGN/METHODS: Seventy-two young women without any symptoms were included to the study. Women underwent pelvic examination when cervical smears for cytology and Ch.tr. were taken and BV tests were performed. Presence of Chlamydia was estimated by direct immunofluorescent method. Subjects included to the study provided information concerning life style, and gynecological complaints. RESULTS: In both BV(+) or Ch.tr.(+) women, abnormal PapTest results were more frequently observed. All those three factors correlated with declared over 5 lifetime sexual partners. Ch.tr. infection correlated with BC pills using, cigarette smoking and presence of the cervical lesions evaluated as glandular ectopy. Abnormal PapTest result was obtained in 12 subjects. Two, the most abnormal cases were described as LSIL and confirmed by direct biopsy as CIN 1, also with coexistence of C. trachomatis infection and positive for BV. CONCLUSIONS: Ch.tr. infection seems to affect more frequently sexually active, smoking, young women using BC pills, with presence of cervical lesion described as clinically unsuspected glandular ectopy, although with occasionally cytological abnormal findings.
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