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  • Title: [A case of transitional cell carcinoma of the renal pelvis with adenocarcinoma producing CEA and CA19-9].
    Author: Matsuoka Y, Ishimaru H, Arai G, Aida J, Okada Y, Ito Y.
    Journal: Hinyokika Kiyo; 2004 Sep; 50(9):637-40. PubMed ID: 15518131.
    Abstract:
    We report a case of invasive renal pelvic tumor with high serum levels of carcinoembryonic antigen (CEA) and carbohydrate antigen (CA 19-9). An 86-year-old man presented with macrohematuria. Retrograde pyelography demonstrated a filling defect in right upper calyx, suspected of renal pelvic tumor. The levels of serum CEA and CA 19-9 were elevated to 28.0 ng/ml and 122 U/ml, respectively. No abnormalities were found in the gastrointestinal tract. Right nephroureterectomy was performed, and histopathological diagnosis was transitional cell carcinoma, grade 2>grade 3, accompanied with adenocarcinoma immuno-stained for CEA and CA19-9. A part of the tumor showed a tubular growth pattern. Both serum levels of CEA and CA 19-9 immediately decreased to the normal range after the operation, but increased again with lung and hepatic metastases.
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