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  • Title: [Secondary surfactant deficiencies in extremely low birth weight premature infants].
    Author: Rivera S, Gaugler C, Langlet C, Villega F, Astruc D, Escande B, Kuhn P, Messer J.
    Journal: Arch Pediatr; 2004 Nov; 11(11):1346-50. PubMed ID: 15519835.
    Abstract:
    Primary deficiency of surfactant is responsible for the respiratory distress syndrome and concerns premature neonates born before 33 weeks of gestation. However, newborns may develop respiratory disorders related to a secondary deficiency or dysfunction of surfactant. We report the course of three extremely low birth weight premature infants who experienced clinical respiratory decompensation at two weeks and showed a marked improvement after exogenous natural surfactant administration.
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