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  • Title: [Role of trehalose and glycogen in the survival of aging Saccharomyces cerevisiae cells].
    Author: Samokhvalov VA, Mel'nikov GV, Ignatov VV.
    Journal: Mikrobiologiia; 2004; 73(4):449-54. PubMed ID: 15521168.
    Abstract:
    The role of the storage carbohydrates trehalose and glycogen in the survival of aging Saccharomyces cerevisiae cells was studied. Culture aging for one week did not reduce cell viability. During this period, the cells accumulated the storage carbohydrates and raised the activity of the glycolytic enzymes hexokinase and phosphofructokinase. However, further aging led to a drastic drop in cell viability and to a decrease in the cellular content of trehalose and glycogen and in the activity of hexokinase and phosphofructokinase. The possible reasons for these changes are discussed.
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