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  • Title: [Bone mineral density in patients with Crohn's disease. Contribution of bone densitometry in 53 cases].
    Author: Bouzaïdi S, Ben Salem M, Mnif N, Ben Hammouda I, Ben Yedder J, Trabelsi S, Moussa A, Jemaa Y, Debbech R, Salem M, Najjar T, Hamza R.
    Journal: Tunis Med; 2004 Aug; 82(8):753-9. PubMed ID: 15532771.
    Abstract:
    Fifty-three patients with Crohn disease were included in a prospective study. Bone mineral density was measured at the femoral neck and lumbar spine by dual-energy X-ray absorptiometry. Ten variables were analyzed in search of an association with bone demineralization; Age, sex, nutritional state, smoking, duration of the disease, hormonal status, inflammatory syndrome, site of disease: ileal, colic or ileocolic, accumulated doses of corticoids and intestinal resection. A bone demineralization was observed in 58.5% of cases. The ileum location and the corticothérapie were predictives of bone demineralization. Crohn disease is a disease at high risk of bone demineralization. Predictors of the bone loss were smoking, long duration of the disease, ileal site and systematic corticotherapy.
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