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  • Title: Anemia in patients on combined androgen block therapy for prostate cancer.
    Author: Qian LX, Hua LX, Wu HF, Sui YG, Cheng SG, Zhang W, Li J, Wang XR.
    Journal: Asian J Androl; 2004 Dec; 6(4):383-4. PubMed ID: 15546035.
    Abstract:
    AIM: To study the effect of combined androgen block therapy on hemoglobin and hematocrit values in patients with prostate cancer. METHODS: One hundred and thirty-six patients with adenocarcinoma of prostate were treated with combined androgen block (orchiectomy and flutamide 250 mg, tid). Complete blood counts were determined before and after 1, 2, 3, 6, 9 and 12 months of therapy. RESULTS: The hemoglobin and hematocrit levels declined significantly in all patients and at all the time points after treatment (P<0.05). CONCLUSION: Prostate cancer patients treated with combined androgen block would develop obvious anemia. Recombinant human erythropoietin can be used to treat patients with severe anemia.
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