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  • Title: Repression and high anxiety are associated with aberrant diurnal cortisol rhythms in women with metastatic breast cancer.
    Author: Giese-Davis J, Sephton SE, Abercrombie HC, Durán RE, Spiegel D.
    Journal: Health Psychol; 2004 Nov; 23(6):645-50. PubMed ID: 15546233.
    Abstract:
    Previous research has provided evidence of autonomic, endocrine, and immunological dysregulation in repressers and a possible association with cancer incidence and progression. Recently published data from the authors' laboratory demonstrated that flatter diurnal cortisol slopes were a risk factor for early mortality in women with metastatic breast cancer. In the current analysis of this same sample (N=91), the authors tested differences at baseline between groups scored using the Weinberger Adjustment Inventory on diurnal cortisol slope and mean cortisol levels. When compared with self-assured and nonextreme groups, the represser and high-anxious groups had a significantly flatter diurnal slope. Diurnal slope was similar for repressers and high-anxious groups. Groups did not differ on mean cortisol levels, nor did they differ on intercept (morning) values.
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