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  • Title: Design, synthesis and anti-microbial activity of 1H-pyrazole carboxylates.
    Author: Sridhar R, Perumal PT, Etti S, Shanmugam G, Ponnuswamy MN, Prabavathy VR, Mathivanan N.
    Journal: Bioorg Med Chem Lett; 2004 Dec 20; 14(24):6035-40. PubMed ID: 15546724.
    Abstract:
    In a SAR study, we have synthesized a few 1H-pyrazole carboxylate related microbicides using Vilsmeier reagent. The anti-microbial screening results of 1H-pyrazole-3-carboxylate are reported here for the first time. The effect of 1H-pyrazole carboxylates on the mycelial growth of plant pathogenic fungi is revealed. The first X-ray structure in the family of microbicidal 1H-pyrazole-4-carboxylates is presented.
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