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Title: Facile synthesis of @-tide beta-strand peptidomimetics: improved assembly in solution and on solid phase. Author: Phillips ST, Piersanti G, Rüth M, Gubernator N, van Lengerich B, Bartlett PA. Journal: Org Lett; 2004 Nov 25; 6(24):4483-5. PubMed ID: 15548056. Abstract: The synthesis of @-tide beta-strand peptidomimetics has been improved such that oligomers now can be obtained from solution- and solid-phase synthesis protocols approaching the efficiency and flexibility of peptide chemistry. These methods enable the synthesis of @-tide oligomers with a variety of amino acids and with lengths up to 13 units. [reaction: see text][Abstract] [Full Text] [Related] [New Search]