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  • Title: Combined transport of water and ions through membrane channels.
    Author: Pohl P.
    Journal: Biol Chem; 2004 Oct; 385(10):921-6. PubMed ID: 15551866.
    Abstract:
    The coupling of ion and water flow through membrane channels is under dispute. Among all human aquaporins only aquaporin-6 exhibits ion channel activity. Whether aquaporin-6 functions also as a water channel cannot yet be determined with confidence. Similarly, a comparison of single-channel water permeabilities from ion channels and aquaporins suggests that ion channels may play a secondary role as water channels. However, the fraction of absorbed fluid that crosses epithelial ion channels still remains to be determined.
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