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  • Title: [High contrast doses for peripheral and cerebral angiography (author's transl)].
    Author: Holik B.
    Journal: Rofo; 1979 Mar; 130(3):275-7. PubMed ID: 155566.
    Abstract:
    Angiography, using a standard method, was carried out on 100 patients with arterial occlusive disease involving the cerebral and/or peripheral vessels. It was shown that contrast medium with a high iodine content could be used in the relatively high dose of 80 ml. with an injection rate of 30 ml/sec. in the cerebral circulation without producing any complications. For pelvic and lower limb arteriography, 80 ml. contrast was injected at a rate of 12 to 18 ml/sec. This was well tolerated, but produced "vascular pain" like all commercially available contrast media. Total contrast amounts reached 300 ml. and 4.8 ml/kg. body weight and were tolerated without any clinical evidence of toxicity. Mild side effects were observed in seven patients, unrelated to the amount of contrast or the type of contrast or the region investigated. These changes resolved rapidly without treatment. As a rule the vessels demonstrated angiographically showed good contrast and were easily seen.
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