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  • Title: Soluble fibrin, C-reactive protein, fibrinogen, factor VII, antithrombin, proteins C and S, tissue factor, D-dimer, and prothrombin fragment 1 + 2 in men with acute myocardial infarction </=45 years of age.
    Author: Saigo M, Waters DD, Abe S, Biro S, Minagoe S, Maruyama I, Tei C.
    Journal: Am J Cardiol; 2004 Dec 01; 94(11):1410-3. PubMed ID: 15566913.
    Abstract:
    To evaluate the contribution of hematologic factors and long-term inflammation to the development of myocardial infarction at a young age, we measured hematologic variables, including soluble fibrin and high-sensitivity C-reactive protein, in 90 patients who had myocardial infarction and 138 controls </=45 years of age. Plasma levels of soluble fibrin and C-reactive protein were significantly higher in patients than in controls. On multivariate regression analysis, soluble fibrin was the strongest predictor of myocardial infarction at a young age.
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