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  • Title: Prevalence of human papillomavirus in Mazandaran Province, Islamic Republic of Iran.
    Author: Hamkar R, Azad TM, Mahmoodi M, Seyedirashti S, Severini A, Nategh R.
    Journal: East Mediterr Health J; 2002 Nov; 8(6):805-11. PubMed ID: 15568458.
    Abstract:
    We report the prevalence of human papillomavirus (HPV) types in 100 cervical biopsy specimens in Mazandaran province. HPV DNA was detected in 78.6% of cervical carcinoma cases, 64.3% of dys/ metaplasia and 9% of normal cases. Significant correlation was found between the presence of HPV DNA and development of cervical carcinoma. HPV types 16 and 18 were detected in 60.6% of HPV-positive cervical carcinoma cases, whereas HPV31 and 33 were found in 21.2%, and HPV6 and 11 in 18.2%. Among HPV-positive dys/metaplasia cases, 55.6% were positive for HPV16 and 18, 22.3% for HPV6 and 11, and 11.1% for HPV31 and 33. Only HPV6 and 11 were detected in 4 (100%) normal biopsy specimens.
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