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  • Title: Furanolabdane diterpenes from Hypoestes purpurea.
    Author: Shen CC, Ni CL, Huang YL, Huang RL, Chen CC.
    Journal: J Nat Prod; 2004 Nov; 67(11):1947-9. PubMed ID: 15568798.
    Abstract:
    Four new furanolabdane diterpenes, hypopurin A (1), hypopurin B (2), hypopurin C (3), and hypopurin D (4), together with eight lignans, alpha-O-methylcubebin, beta-O-methylcubebin, hinoquinin, helioxanthin, 7-hydroxyhinokinin, dehydroxycubebin, justicidine E, and (-)-hibalactone, as well as two triterpenes, lupeol and betulin, were isolated from the dried aerial part of Hypoestes purpurea. The structures of 1-4 were elucidated mainly on the basis of NMR and MS. Compound 1 was found to be moderately cytotoxic toward the KB cell line with an IC(50) value of 9.4 microM.
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