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  • Title: [Extended transsphenoidal approach to giant tumors in sellar and clival area].
    Author: Wang RZ, Ren ZY, Su CB, Yang Y, Tao W, Ma WB, Yin J.
    Journal: Zhonghua Yi Xue Za Zhi; 2004 Oct 17; 84(20):1693-7. PubMed ID: 15569427.
    Abstract:
    OBJECTIVE: To explore the effects of extended transsphenoidal approach, a new approach for removing giant tumors in sellar and clival area. METHODS: Twenty-eight patients, 19 males and 9 females, aged 17 - 67 with a mean age of 47.8, with a mean history of 6.2 years, 13 with invasive giant pituitary adenoma, 10 with chordoma, 2 with giant cell tumor of bone, 2 with pituitary metastatic tumor, and 1 with pituitary endocrinal carcinoma underwent operation by extended transsphenoidal approach. The tumors were 3.0 - 5.5 cm in size. In 2 cases the tumor extended to the base of the frontal lobe, 7 tumors involved the cavernous sinus, and 19 extended to clivus. RESULTS: The tumor was totally removed in 19 patients, removed subtotally in 6 patients, and removed partially in 3 patients. Postoperative follow-up was performed for 6 months to 4 years. No recurrence occurred except for enlargement of 2 pituitary metastatic tumors and 1 chordoma. CONCLUSION: Extended transsphenoidal approach satisfactorily reaches and helps remove the giant tumors in sellar and clival area without severe complication.
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