These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Antitumor effect of natural avermectins].
    Author: Driniaev VA, Mosin VA, Krugliak EB, Sterlina TS, Novik TS, Ermakova NV, Kublik LN, Levitman MKh, Shaposhnikova VV, Korystov IuN.
    Journal: Antibiot Khimioter; 2004; 49(5):8-10. PubMed ID: 15573897.
    Abstract:
    The effects of the natural avermectin complex, aversectin C and individual avermectin B1 on the growth of ascitic and solid transplantable tumors in animals were studied. The results showed for the first time that both aversectin C and avermectin B1 possessed marked antitumor activity. In subtoxic doses aversectin C significantly inhibited the growth of P388 lymphoid leukemia and Ehrlich carcinoma, both ascitic and solid ones. In some administration regimens aversectin C inhibited the tumor growth by 70 to 80%. The highest effect of aversectin C was observed after its intraperitoneal administration. Avermectin B1 inhibited the growth of solid Ehrlich carcinoma and carcinoma 755.
    [Abstract] [Full Text] [Related] [New Search]