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  • Title: Epstein-Barr virus positivity in primary vaginal lymphoma.
    Author: Domingo S, Perales A, Torres V, Alcaraz MJ, Pellicer A.
    Journal: Gynecol Oncol; 2004 Dec; 95(3):719-21. PubMed ID: 15581989.
    Abstract:
    BACKGROUND: Primary non-Hodgkin lymphoma (NHL) of the vagina is a rare location. Its association with the Epstein-Barr virus (EBV) has been only reported in another case. We present a new case, emphasizing the oncogenetic relevance of EBV. CASE REPORT: A 45-year-old woman with a pelvic pain revealed in her vaginal inspection a thick and hard vaginal plug with a "paving stone" appearance. The biopsy reported a vaginal non-Hodgkin lymphoma type B of intermediate cell, with positive result for EBV. After treatment, a complete remission was obtained. CONCLUSION: The EBV is the main responsible for the non-Hodgkin lymphoma; classified as a group I carcinogen, it has been associated with a variety of neoplastic tumors, although it is unusual with extranodal type B diffuse lymphoma.
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