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  • Title: Molluscicidal and cercaricidal efficacy of Acanthus mollis and its binary and tertiary combinations with Solanum nigrum and Iris pseudacorus against Biomphalaria alexandrina.
    Author: Ahmed AH, Rifaat MM.
    Journal: J Egypt Soc Parasitol; 2004 Dec; 34(3):1041-50. PubMed ID: 15587327.
    Abstract:
    Molluscicidial activity of leaves of Acanthus mollis against Biomphalaria alexandrina were evaluated. Its petroleum ether extract (LC50 values = 6.92 mg/L) was more potent than Solanum nigrum and Iris pseudacorus extracts. A binary combination (1:1) of A. mollis and S. nigrum, as well as, a binary combination (1:1) of A. mollis and I. pseudacorus extracts showed additive effect on snails (24 hr LC50: 5.09 mg/l and 3.76 mg/l respecttively). A tertiary combination (1:1:1) of A. mollis, S. nigrum and I. pseudacorus extracts (24 hr LC50: 4.01 mg/l) showed good result. Also, petroleum ether extract of A. mollis leaves killed Schistosoma mansoni cercariae at concentrations of 20, 10 and 5 mg/l within 30, 45 min. and an hour respectively. Mortality increased with increasing exposure time and concentration.
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