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  • Title: Reduction of carboxyhaemoglobin levels in the venous blood of cigarette smokers following the administration of carbogen.
    Author: Macdonald G, Kondor N, Yousefi V, Green A, Wong F, Aquino-Parsons C.
    Journal: Radiother Oncol; 2004 Dec; 73(3):367-71. PubMed ID: 15588884.
    Abstract:
    Cigarette smokers have high carboxyhaemoglobin levels which can promote tumour radioresistance. Inhalation of carbogen gas shortens the half-life of carboxyhaemoglobin, increasing tumour radiosensitivity in animal models. Breathing 2.5% carbogen for 30 min results in a greater reduction in venous blood COHb levels than breathing 5% carbogen for 7 min.
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