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  • Title: Efficient antioxidant capacity against lipid peroxide levels in healthy elderly of Mexico City.
    Author: Sánchez-Rodríguez MA, Retana-Ugalde R, Ruíz-Ramos M, Muñoz-Sánchez JL, Vargas-Guadarrama LA, Mendoza-Núñez VM.
    Journal: Environ Res; 2005 Mar; 97(3):322-9. PubMed ID: 15589241.
    Abstract:
    We evaluated antioxidant activity against lipid peroxide levels (LPO) in healthy elderly and adults of Mexico City in comparison with a population of a rural area. The study included free-living subjects: 38 adults aged <60 years and 129 older subjects aged > or = 60 years of urban Mexico City in addition to 37 adults aged <60 years and 88 older subjects aged > or = 60 years of rural area (Actopan, Hidalgo State, Mexico). LPO were observed as higher in adults and elderly of the urban area than among rural subjects (P<0.01), although LPO levels were similar in rural adults and elderly (P>0.05); conversely, in urban area levels were higher in the elderly than in adults (P<0.01). On the other hand, the superoxide dismutase in urban elderly was higher than that in rural elderly (P<0.05) but similar between urban adults and urban elderly (P>0.05). Total oxidant status in urban elderly was higher than that in rural elderly (P<0.01). Our findings allow us to conclude that the urban elderly (residents of Mexico City) have higher oxidative stress than the rural-dwelling elderly, though the urban elderly have efficient antioxidant capacity as a response to elevated LPO.
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