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  • Title: Interphotoreceptor retinoid-binding protein in the Golgi apparatus of monkey foveal cones. Electron microscopic immunocytochemical localization.
    Author: Carter-Dawson L, Burroughs M.
    Journal: Invest Ophthalmol Vis Sci; 1992 Apr; 33(5):1589-94. PubMed ID: 1559757.
    Abstract:
    The presence of interphotoreceptor retinoid-binding protein (IRBP) in the Golgi apparatus of monkey cone photoreceptors was examined by electron microscopic immunocytochemistry. Intracellular labeling for IRBP was light to moderate over the Golgi complex of foveal and peripheral cones in the retinas of all four monkeys examined. Composite drawings of two to seven serial sections of inner segments indicated that the highest density of intracellular labeling occurred over the Golgi apparatus. The labeling density over the Golgi complex was 8.5-29-fold higher than that over a comparable area of inner segment cytoplasm. The presence of immunolabel for IRBP in the Golgi apparatus supported the findings of in situ hybridization studies that cone photoreceptors can synthesize IRBP.
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