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  • Title: Rapidly progressive glomerulonephritis: current and evolving treatment strategies.
    Author: Little MA, Pusey CD.
    Journal: J Nephrol; 2004; 17 Suppl 8():S10-9. PubMed ID: 15599880.
    Abstract:
    Rapidly progressive glomerulonephritis (RPGN) must be diagnosed and treated quickly to prevent irreversible organ injury. The commonest cause of RPGN is anti-neutrophil cytoplasm antibody (ANCA) associated small vessel vasculitis, and the most severe is anti-glomerular basement membrane (GBM) antibody disease. In this review we address pathogenesis, diagnosis, treatment and outcome in these two entities, with emphasis on novel therapies.
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