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  • Title: [The effects of traditional Chinese medicines on the adherence of Streptococcus mutans to salivary acquired pellicle in vitro].
    Author: Huang Z, Zhou X, Li J, Liu T, Li H, Zhu B.
    Journal: Sichuan Da Xue Xue Bao Yi Xue Ban; 2003 Jan; 34(1):135-7. PubMed ID: 15600205.
    Abstract:
    OBJECTIVES: To investigate the effects of traditional Chinese medicines on the preliminary adherence of Streptococcus mutans to salivary acquired pellicles. METHODS: The hydroxyapatites beads were coated by saliva to form S-HA, an in vitro model of experimental pellicle. Streptococcus mutans was chosen as the experiment strain, and radiolabeled with 3H-thymidine. Two parts of adherence inhibit study were carried on with medicines pretreated S-HA and medicines pretreated bacteria. The numbers of 3H-thymidine labeled bacteria attached to S-HA were counted by scintillation counting to indicate the amount of adherence. RESULTS: It was found that most of the traditional Chinese medicines tested could inhibit the adherence to S-HA to different extent, especially the Galla Chinensis, which has significant inhibitory action. CONCLUSION: Galla Chinensis may be a prospective medicine to inhibit the cariogenic bacteria's preliminary adherence to salivary acquired pellicles.
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