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  • Title: Base-sequence-dependent sliding of proteins on DNA.
    Author: Barbi M, Place C, Popkov V, Salerno M.
    Journal: Phys Rev E Stat Nonlin Soft Matter Phys; 2004 Oct; 70(4 Pt 1):041901. PubMed ID: 15600429.
    Abstract:
    The possibility that the sliding motion of proteins on DNA is influenced by the base sequence through a base pair reading interaction, is considered. Referring to the case of the T7 RNA-polymerase, we show that the protein should follow a noise-influenced sequence-dependent motion which deviate from the standard random walk usually assumed. The general validity and the implications of the results are discussed.
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