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  • Title: Management of neuropathic pain following treatment for breast cancer in the absence of recurrence: a challenge for the radiation oncologist.
    Author: Clubb B.
    Journal: Australas Radiol; 2004 Dec; 48(4):459-65. PubMed ID: 15601324.
    Abstract:
    This report reviews various management options for treatment-induced neuropathic pain in breast cancer. First-line options include tricyclic antidepressants and anticonvulsant drugs. Opioids should be prescribed according to published guidelines. Second-line treatments include lignocaine, mexiletine and ketamine. Sympatholytic therapies are available to patients with features of chronic regional pain syndrome. Anti-inflammatory agents are used for neurogenic inflammation. Surgical interventions are considered for refractory neuropathic pain. Interdisciplinary management is appropriate when persisting pain causes physical and psychosocial disabilities.
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