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  • Title: [Outcome of the treatment for laryngeal carcinoma by partial laryngectomies].
    Author: Pajor A, Kopczyński J, Gryczyński M.
    Journal: Otolaryngol Pol; 2004; 58(4):757-64. PubMed ID: 15603386.
    Abstract:
    The aim of the study was to retrospectively evaluate the results of treatment for early laryngeal carcinoma in a group of 325 patients who underwent from 1980 to 1997 partial laryngectomies. The most often type of operation was cordectomy--51.1%, then frontolateral/frontoanterior laryngectomy--20.9%, vertical laryngectomy--15.1%, supraglottic horizontal laryngectomy--8%, hemilaryngectomy--4.9%. Estimate of survival time, from surgery to first oncologic failure, was obtained with the life-table method. As a failure we considered local and regional recurrence, distant metastasis, second primary neoplasm and spread of disease. The probability of disease-free survival for all partial laryngectomies reached 81.5%, 79.5% and 60.3% at 3, 5 and over 5 years, respectively. The rates of five-year and over 5 year disease-free survival for each type of operation were: for cordectomy--82.3% and 72.3%, for frontolateral/frontoanterior laryngectomy--74.0% and 45.2%, for vertical laryngectomy--87.6% and 60.6%, for hemilaryngectomy--86.2% and 59.7%, for supraglottic horizontal laryngectomy--53.8% and 29.9%, respectively. The comparison between survival rates, by the log-rank test, revealed statistical difference between supraglottic horizontal laryngectomy and following operations: cordectomy (p < 0.001), vertical laryngectomy (p < 0.01), hemilaryngectomy (p < 0.05). The differences between other types of laryngectomy were not significant statistically. The best results in treatment of laryngeal carcinoma by partial laryngectomies were achieved by operations in vertical plane (cordectomy, vertical laryngectomy and hemilaryngectomy), the less positive--by operations in horizontal plane (supraglottic horizontal laryngectomy).
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