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  • Title: Longterm results in surgical removal of subfoveal choroidal neovascularization in age-related macular degeneration.
    Author: Guthoff R, Schrader W.
    Journal: Acta Ophthalmol Scand; 2004 Dec; 82(6):686-90. PubMed ID: 15606464.
    Abstract:
    PURPOSE: This study aimed to analyse visual outcome, surgical complications and recurrence rates 3 years after removal of subretinal choroidal neovascularization (CNV) in patients with age-related macular degeneration (AMD). METHODS: The study involved a retrospective analysis of 50 eyes of 50 patients who underwent surgical removal of CNV in AMD between February 1996 and June 1998. The minimum follow-up period was 36 months. Improvement or worsening of visual acuity (VA) was defined as a change of more than two lines. RESULTS: The mean reduction in VA was 2.2 +/- 6.9 lines. Visual acuity improved in 12 eyes, remained stable in 16 eyes and worsened in 22 eyes. Recurrence of CNV occurred in three eyes. CONCLUSION: After surgical excision of age-related subfoveal CNV, VA improved or stabilized in a large group of patients. Considering the development of VA and the low recurrence rate, surgical treatment seems to be beneficial compared to the natural course of CNV over a longterm follow-up of more than 3 years.
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