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  • Title: [Diagnosis of Mycobacterium ulcerans infections in French Guiana].
    Author: Prévot G, Marsollier L, Carbonelle B, Pradinaud R, Coupié P, Sainte-Marie D, Bourreau E, Launois P.
    Journal: Presse Med; 2004 Dec 04; 33(21):1516. PubMed ID: 15614174.
    Abstract:
    THE SITUATION: Buruli's ulcer is a severe necrotic cutaneous infection due to Mycobacterium ulcerans. It is a major public health problem in developing countries. FROM A CLINICAL POINT OF VIEW: The early stage of the infection corresponds to a painless cutaneous nodule, whereas the late stage corresponds to ulceration with detachment of the edges. There is currently no other treatment than surgical excision combined with heat therapy. FROM A DIAGNOSTIC POINT OF VIEW: Three methods can be used: direct examination of swabs stained according to Ziehl-Neelsen's method, culture in specific medium at 32 degrees C and the polymerization chain reaction assay (PCR). The latter is the technique of choice.
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