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  • Title: Total hemolytic complement values in normal and diseased dog populations.
    Author: Wolfe JH, Halliwell RE.
    Journal: Vet Immunol Immunopathol; 1980 Aug; 1(3):287-98. PubMed ID: 15615062.
    Abstract:
    The optimum conditions for handling and storage of canine sera for total hemolytic complement assays were assessed. Sera from 113 normal dogs and 217 clinical admissions to the University of Pennsylvania Veterinary Hospital were assayed for total hemolytic complement levels. Normal sera had a mean value of 185 CH50 units. Sera from animals with systemic lupus erythematosus and hemorrhagic gastroenteritis, had significantly lower mean levels of complement than the normal group. Sera from dogs with generalized demodectic mange, tumors, various inflammatory diseases, hypothyroidism, seborrhea, and rheumatoid arthritis had values significantly higher than the normal population.
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