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  • Title: [The changes and relation among platelet function, plasma heparin and anti-coagulation-III: activity in patients with hemorrhagic fever with renal syndrome].
    Author: Wei L, Pan X, Yu Y, Lu Q.
    Journal: Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi; 1997 Jun; 11(2):163-5. PubMed ID: 15619827.
    Abstract:
    Blood platelet count (BPC), platelet adhesive rate (PAdT), platelet aggregate rate (PAgT), plasma heparin and anti-coagulation-III: activity (AT-III: alpha) were determined in 55 cases with hemorrhagic fever with renal syndrome (HFRS). In these patients, decreased BPC, defect PAdT, PAgT, increased plasma heparin as well as decreased AT-III: a were found, moreover, these changes were much notable in patients with severe type. A positive correlation existed between plasma heparin and BPC, PAdT, PAgT in cases with 80% AT-III: alpha or above (r values were -0.4344, -.7157 and -0.5547 respectly, p<0.01). The results suggested that plasma heparin may be one of factors resulting in decreased BPC and defect platelet function in HFRS patients with 80% AT-III: alpha or above.
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