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  • Title: Ent-kauranoids from Isodon rubescens var. taihangensis.
    Author: Han QB, Li RT, Li ML, Mou YK, Tian QE, Li SW, Sun HD.
    Journal: J Asian Nat Prod Res; 2005 Feb; 7(1):31-6. PubMed ID: 15621599.
    Abstract:
    Two new compounds, rubescensins Q and R (1 and 2), and a new acetonide derivative (3) of lasiodonin, together with thirteen known analogues, oridonin (4), ponicidin (5), wikstroemioidin B (6), lasiodonin (7), lasiokaurin (8), enmenol (9), 1-O-beta-D-glucopyranosyl-enmenol (10), trichokaurin (11), the acetonide of maoyecrystal F (12), rabdoternins A-D (13-16), have been isolated from Isodon rubescens var. taihangensis. The structures of the new compounds were elucidated on the basis of spectroscopic methods, especially the 2D NMR spectral analysis. Compound 3 exhibited cytotoxicity against K562, Bcap37, CA, CNE, BIU87, BGC823, and HeLa cell lines.
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