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  • Title: Revisit of metformin treatment in polycystic ovarian syndrome.
    Author: Lam PM, Cheung LP, Haines C.
    Journal: Gynecol Endocrinol; 2004 Jul; 19(1):33-9. PubMed ID: 15625771.
    Abstract:
    Polycystic ovary syndrome (PCOS) is a common endocrinopathy in women; its traditional pharmacological therapy mainly addresses short-term symptom control and does not correct the associated long-term metabolic risks. Recently, there has been increasing evidence that insulin resistance has an important implication in the pathogenesis of PCOS and that insulin-sensitizing drugs are a useful therapeutic approach. Therefore this review aims to discuss the current evidence on the use of metformin, a commonly used insulin-sensitizing agent, in treating both the short-term and the long-term problems of women with PCOS.
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