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  • Title: [Lipids and homocysteine level in juvenile idiopathic arthritis].
    Author: Urban M, Pietrewicz E, Górska A, Głowińska B.
    Journal: Pol Merkur Lekarski; 2004 Sep; 17(99):235-8. PubMed ID: 15628048.
    Abstract:
    We investigated serum levels of lipids (total cholesterol, HDL-cholesterol, LDL-cholesterol, triglicerides), homocysteine, C-reactive protein (CRP) in 25 children with juvenile idiopathic arthritis (JIA) and 15 healthy control. We found statistically significant increase of total cholesterol, LDL-cholesterol, triglicerides (p<0.05) and decreased of HDL-cholesterol (p<0.05) in JIA patients compare to control group. Homocysteine correlated significantly with total cholesterol (r=0.47; p<0.05) and with LDL-cholesterol (r=0.53; p<0.05). In JIA children we found adverse lipids profile and increase of homocysteine level which may lead to early atherosclerosis.
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