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  • Title: Comparison of biochemical with radiological findings in renal osteodystrophy.
    Author: Moorhead JF, Varghese Z, Tatler GL, Baillod RA, Wills MR.
    Journal: Ann Clin Biochem; 1975 May; 12(3):126-31. PubMed ID: 15637920.
    Abstract:
    In a group of 121 adult patients with end-stage chronic renal failure who had been undergoing maintenance haemodialysis for up to 10 years a number of biochemical variables have been measured and related to a set of objective radiological changes in the same patients. The changes in plasma calcium, magnesium, phosphate, total protein, and albumin concentration did not distinguish the patients who were grouped on a radiological basis. Plasma alkaline phosphatase activity increased with the severity of the radiological findings but did not provide a sensitive discriminatory index between the different radiological groups. Plasma hydroxyproline concentration was found to be more sensitive than plasma alkaline phosphatase activity in detecting a radiological abnormality in some of the patients.
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