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  • Title: New camptothecin and ellagic acid analogues from the root bark of Camptotheca acuminata.
    Author: Zhang Z, Li S, Zhang S, Liang C, Gorenstein D, Beasley RS.
    Journal: Planta Med; 2004 Dec; 70(12):1216-21. PubMed ID: 15643560.
    Abstract:
    As part of a study on chemical constituents of Camptotheca species, one new natural camptothecin analogue (2), two new alkaloids (3, 4), one new ellagic acid analogue (5), and 19 known compounds (1, 6-23) have been isolated from the root bark, stem bark, fruits, and leaves of Camptotheca acuminata Decaisne. The structures of 2-5 were determined from spectral data to be 10-methoxy-20-O-acetylcamptothecin (2), 20-O-beta-glucopyranosyl 18-hydroxycamptothecin (3), 20-formylbenz indolizino [1,2-b]quino-line-11(13H)-one (4), and 3,4-methylenedioxy-3'-O-methyl-5'-hydroxyellagic acid (5).
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