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  • Title: Colonic perforation in collagenous colitis: an unusual complication.
    Author: Bohr J, Larsson LG, Eriksson S, Järnerot G, Tysk C.
    Journal: Eur J Gastroenterol Hepatol; 2005 Jan; 17(1):121-4. PubMed ID: 15647652.
    Abstract:
    Collagenous colitis is generally regarded as a benign disease with few serious complications. We report two women with collagenous colitis who presented with colonic perforation, one spontaneously and one 7 days after a barium enema, and a review of the literature. Including the present cases, 13 patients with collagenous colitis and colonic perforation have been reported, in two patients spontaneously and in 11 patients after a colonoscopy or barium enema. All were operated on except one patient who recovered after medical treatment. The pathogenesis of this complication is unknown. We propose that there might be a connection between mucosal tears and colonic perforation in collagenous colitis.
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