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  • Title: Detection of herpesvirus-6A in a case of subacute cerebellitis and myoclonic dystonia.
    Author: Borghi E, Pagani E, Mancuso R, Delbue S, Valli M, Mazziotti R, Giordano L, Micheli R, Ferrante P.
    Journal: J Med Virol; 2005 Mar; 75(3):427-9. PubMed ID: 15648060.
    Abstract:
    This is a case study of a child who developed roseola infantum first, then varicella, and was later affected by acute cerebellar syndrome, severe truncal ataxia, and myoclonic dystonia. Human herpesvirus 6 (HHV-6) A and B were detected in the cerebrospinal fluid (CSF) and peripheral blood, respectively, upon ataxia onset. The intricacy of this case suggests multifaceted conclusions ranging from the need for a multidirectional approach to neurological diseases, to confirmation of a more pronounced neurotropism of HHV-6A and a possible role of viruses in myoclonic dystonia syndrome, although this last hypothesis should be confirmed by larger studies.
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