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  • Title: [Galectin-3 in differential diagnosis and prognosis of follicular tumors of the thyroid gland].
    Author: Iushkov PV, Antonova SS, Bartolazzi A.
    Journal: Arkh Patol; 2004; 66(6):39-42. PubMed ID: 15648166.
    Abstract:
    Differential diagnosis between follicular thyroid tumours (FTT) is difficult both at cytological and histological levels. Infiltrative growth is authentic criterion of malignancy. Immunohistochemical reaction (PAP-method) with galectin-3 antibodies was used. The results allow to make differential diagnosis of thyroid tumours before the surgery. Immunohistochemical identification of galectin-3 in the tissue of follicular adenomas with grave dysplasia and follicular carcinoma is an unfavourable prognostic sign.
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