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Title: [Overtraining syndrome]. Author: Guezennec CY. Journal: Bull Acad Natl Med; 2004; 188(6):923-30; discussion 931. PubMed ID: 15651422. Abstract: Numerous studies have shown that enhanced physical load can result in an overtraining syndrome, with a decreased capacity for physical exercise and behavioral disturbances. Overtraining is caused by an imbalance between energy intake and output, and is facilitated by chronobiological and psychological stress. These factors are responsible for hormonal changes such as a decrease in gonadal steroids or in the hypothalamo-pituitary-adrenal axis. These metabolic and hormonal influences are lead to change in brain neuromediator activity, such as reduced monamine and increased serotonin levels. Experimental data indicate that these neuromediator changes are responsible more for behavioral changes than for decreased physical performance.[Abstract] [Full Text] [Related] [New Search]