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  • Title: Not just another hole in the wall: understanding intercellular protein trafficking.
    Author: Gallagher KL, Benfey PN.
    Journal: Genes Dev; 2005 Jan 15; 19(2):189-95. PubMed ID: 15655108.
    Abstract:
    Development and differentiation of multicellular organisms requires cell-to-cell communication. In plants direct signaling and exchange of macromolecules between cells is possible through plasmodesmata. Recently direct exchange of membrane-bound vesicles and organelles has been demonstrated between animal cells through formation of cytoplasmic bridges (tunneling nanotubes) in vitro. Here we review recent developments in cell-to-cell trafficking of macromolecules in plants and animals.
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