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  • Title: Myoepithelial carcinoma ex pleomorphic adenoma of salivary glands: a problematic diagnosis.
    Author: Said S, Campana J.
    Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2005 Feb; 99(2):196-201. PubMed ID: 15660092.
    Abstract:
    We report the case of a 77-year-old woman who presented with a 6-year history of pleomorphic adenoma with multiple recurrences. Despite the clinical suspicion of a malignant process, the detection of myoepithelial carcinoma ex pleomorphic adenoma was not achieved by means of a preoperative biopsy or a frozen section removed intraoperatively, as the lesion only showed mild cytological atypia with no frank malignant features. Only a thorough evaluation of the resected tumor enabled the diagnosis of a malignancy. We discuss the difficulties that may be encountered in attempting to diagnose these rare myoepithelial lesions by means of small biopsy specimens.
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