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  • Title: Ratio between the contents of 11-dehydrocorticosterone and corticosterone after acute and repeated stress: effect of dehydroepiandrosterone sulfate.
    Author: Obut TA, Ovsyukova MV, Cherkasova OP.
    Journal: Bull Exp Biol Med; 2004 Aug; 138(2):137-9. PubMed ID: 15662454.
    Abstract:
    Acute stress was accompanied by reduction of 11-dehydrocorticosterone to corticosterone in male rats. The reverse reaction predominated during repeated stress and increased after administration of dehydroepiandrosterone sulfate. Treatment with mu-opioid receptor antagonist naltrexone in a dose of 0.1 mg/kg 20 min before administration of dehydroepiandrosterone sulfate abolished this effect.
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