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  • Title: Effect of wavelength on low-intensity laser irradiation-stimulated cell proliferation in vitro.
    Author: Moore P, Ridgway TD, Higbee RG, Howard EW, Lucroy MD.
    Journal: Lasers Surg Med; 2005 Jan; 36(1):8-12. PubMed ID: 15662631.
    Abstract:
    BACKGROUND AND OBJECTIVES: There exist contradictory reports about low-intensity laser light-stimulated cell proliferation. The purpose of this study was to determine the effect of wavelength on proliferation of cultured murine cells. STUDY DESIGN/MATERIALS AND METHODS: Proliferation of primary cell cultures was measured after irradiation with varying laser wavelengths. RESULTS: Fibroblasts proliferated faster than endothelial cells in response to laser irradiation. Maximum cell proliferation occurred with 665 and 675 nm light, whereas 810 nm light was inhibitory to fibroblasts. CONCLUSIONS: These observations suggest that both wavelength and cell type influence the cell proliferation response to low-intensity laser irradiation.
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