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  • Title: Cortical thickness of the frontopolar area in typically developing children and adolescents.
    Author: O'Donnell S, Noseworthy MD, Levine B, Dennis M.
    Journal: Neuroimage; 2005 Feb 15; 24(4):948-54. PubMed ID: 15670671.
    Abstract:
    The development of the frontopolar cortex (FPC) through late childhood and adolescence was investigated using measures of cortical thickness. T(1)-weighted structural MRIs from 35 typically developing participants aged 8-20 years were used to construct 3D models of the brain, from which cortical thickness was measured. There was a significant inverse association between age and cortical thickness, such that cortical thickness decreased as age increased between 8 and 20 years. There was no effect of laterality or gender on cortical thickness.
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