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  • Title: [Fluorescence angiography in the diagnosis of pigment-free melanomas of the choroid].
    Author: Brovkina AF, Skliarova NV, Iurovskaia NN.
    Journal: Vestn Oftalmol; 2004; 120(6):8-11. PubMed ID: 15678660.
    Abstract:
    The ophthalmoscopic and angiographic patterns of 52 patients with pigment-free melanomas of the choroid, aged 27 to 73 were investigated. the mean age of examinees was 52. The prominence of tumors ranged from 1.3 to 6.5 mm. All patients underwent standard ophthalmoscopic general-clinical examinations. The tumor sizes were verified echographically. Fluorescence angiography was made according to the commonly used technique of serial pictures with computer processing. Diagnostically valuable angiographic signs were defined: contrasting of tumor vessels, spotty nature of fluorescence, beginning of fluorescence (arterial phase), pick of fluorescence (late venous phase), intensification velocity of fluorescence, late fluorescence, angiopathy of retinal vessels, large choroidal vessels and tumor-associated epitheliopathy of retina (small pigment foci, druses and hypofluorescence). Considering the research results, fluorescence angiography can be regarded as a principle diagnostic tool in pigment-free melanomas of the choroid.
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