These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: On the structural basis of peptide-bond formation and antibiotic resistance from atomic structures of the large ribosomal subunit.
    Author: Steitz TA.
    Journal: FEBS Lett; 2005 Feb 07; 579(4):955-8. PubMed ID: 15680981.
    Abstract:
    The atomic structures of the large ribosomal subunit from Haloarcula marismortui and its complexes with substrates and antibiotics have provided insights into the way the 3000 nucleotide 23S rRNA folds into a compact, specific structure and interacts with 27 ribosomal proteins as well as the structural basis of the peptidyl transferase reaction and its inhibition by antibiotics. The structure shows that the ribosome is indeed a ribozyme.
    [Abstract] [Full Text] [Related] [New Search]