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  • Title: CD45 knockout mice, diet, and colitis: in the absence of CD45, colitis follows dietary changes.
    Author: Lópeza MC, Holmes N.
    Journal: Ann N Y Acad Sci; 2004 Dec; 1029():355-7. PubMed ID: 15681780.
    Abstract:
    Healthy CD45 KO mice show a Th2-type cytokine secretion profile in their small intestines. Dietary supplementation with human infant formula induced colitis and a shift toward a Th1-type profile, suggesting that diet can alter cytokine secretion.
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