These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Effect of photodynamic therapy combined with interstitial chemotherapy for gliomas].
    Author: Chen LF, Ke YQ, Yang ZL, Wang SQ, Xu RX.
    Journal: Di Yi Jun Yi Da Xue Xue Bao; 2005 Jan; 25(1):116-8. PubMed ID: 15684017.
    Abstract:
    OBJECTIVE: To investigate the therapeutic effect of photodynamic therapy (PDT) combined with interstitial chemo- therapy on gliomas after microsurgery. METHODS: Twenty-eight patients with glioma received microsurgery for glioma resection as much as possible, during which PDT was carried out and an Ommaya bursa implanted into the cavity left by the resected tumor. PDT was performed again 24 h after the operation and carmustine injected into the Ommaya bursa for interstitial chemotherapy at the different time after the operation. The follow-up study lasted for 2 years. RESULTS: Two of the 28 patients had relapse of glioma within 1 year after the operation, with the 1-year survival rate of 89.3% (25/28) and 2-year survival rate of 65.7% (17/28). CONCLUSIONS: PDT combined with interstitial chemotherapy following microsurgery provides a safe and effective treatment of glioma, which can inhibit glioma growth, decrease the recurrence rate, prolong the patients' survival and improve their quality of live.
    [Abstract] [Full Text] [Related] [New Search]