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  • Title: [Tuberculoma and tuberculous meningeal-radiculitis with paradoxical progression during treatment].
    Author: Rabar D, Issartel B, Petiot P, Boibieux A, Chidiac C, Peyramond D.
    Journal: Presse Med; 2005 Jan 15; 34(1):32-4. PubMed ID: 15685096.
    Abstract:
    INTRODUCTION: Neuromeningeal tuberculosis of deleterious, paradoxical, progression despite appropriate antibiotic therapy is rare. OBSERVATION: An immunocompetent woman exhibited an immediately disseminated form of tuberculosis with progressive neurological involvement associating expanding intracranial tuberculomas and meningeal-radiculitis despite adapted anti-tuberculosis quadritherapy. DISCUSSION: During anti-tuberculosis therapy clinical worsening is rare, particularly when 2 different manifestations are associated and the worsening occurs in an immunocompetent patient. This possibility should be systematically evoked in such cases. The explanation of this phenomenon is still unclear.
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